![]() ![]() NSAID drugs purchased OTC and prescription NSAIDs have recommended dose levels and durations printed on the label. Studies of older adults show that those with long-term chronic NSAID use increase their risk of:Ĭhronic NSAID use also worsens many diseases, including heart disease and high blood pressure. Long-term use of NSAIDs has greater risk of potential side effects, especially for older people. Many medical professional societies recommend using NSAIDs with caution at the lowest effective dose for the shortest possible time. When taking an NSAID for a longer time, your doctor should monitor you. ![]() The Cleveland Clinic advises that you not use an OTC NSAID for more than three days for fever and 10 days for pain. The effect can be serious if you also take blood thinners like warfarin (Coumadin). ![]() Small cuts may take longer to stop bleeding. This may cause you to bruise more easily. NSAIDs can reduce your blood’s ability to clot. If you have symptoms of a generalized allergic reaction, seek emergency medical care. The foundation advises that if you already have decreased kidney function, you should avoid NSAIDs. The effects on the kidneys were found to be dependent on dose.Īccording to the National Kidney Foundation, NSAIDs may cause an increased risk of sudden kidney failure or kidney damage. Army soldiers using NSAIDs found small but significant increases in the risk of kidney problems. Other kidney problems are less common.Ī large 2019 study of U.S. The most common NSAID kidney problem is fluid retention, like swollen ankles and feet. On average, NSAIDs can increase blood pressure by 5 millimeters of mercury (mmHg). NSAIDs may also reduce the effect of some blood pressure medications. Increased blood pressureĪll NSAIDS can increase your blood pressure whether or not you already have high blood pressure ( hypertension). The FDA warning also says this risk occurs whether or not you have other risk factors for heart disease and stroke. There’s also more likely risk at higher doses. The risk may increase if you use NSAIDs longer. The warning on all NSAID labels notes that the increased risk can occur in the first weeks of NSAID use. ![]() In July 2015, the Food and Drug Administration (FDA) strengthened its warning for all NSAIDs except aspirin about the increased risk of heart attack and stroke. Heart attack and strokeĮxcept for aspirin, NSAIDs can increase your risk for high blood pressure, stroke, or heart attack. They’re thought to be able to reduce stomach problems. NSAIDs that release nitric oxide are under development. You can lessen stomach side effects by taking NSAIDs with food, milk, or a drug that blocks acid production ( antacid).ĭrinking alcohol when taking NSAIDs can increase your risk for internal bleeding. Stomach problems are the most common side effect of NSAIDs. Here are some of the possible side effects: Stomach problems Mild side effects may be countered by lowering the NSAID dose, or taking an additional drug to counter the side effect. Older people and those with some chronic illnesses may have increased risk for side effects from NSAIDs. NSAIDs, like other drugs, have the risk of side effects. ![]()
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